Hebrew University Researchers Introduce Image-Guided Computational Holographic Wavefront Shaping, Offering Fast and Versatile Solutions for Complex Imaging Challenges
A new study has made significant progress in quantum computing through photonic-measurement-based quantum computation. Their innovative method uses high-dimensional spatial encoding to create large cluster states more efficiently, addressing key challenges in scalability and computation speed. This paves the way for faster, resource-efficient, and fault-tolerant quantum computers.
A new perspective work reveals insights into the development of bacterial biofilms, highlighting how these communities adapt to environmental stress through complex interactions between physical and biological processes occurring in the surrounding environment. The research could have broad implications for fields such as medicine, environmental science, and industry.
A new study reveals that reprogramming specialized cells to become different types of cells, a key process in regenerative medicine, faces a major hurdle. The challenge lies in the DNA methylation patterns of the cells, which are like cellular "memory" markers. This study reveals that these patterns often prevent reprogrammed cells from fully adopting their new identities, limiting their effectiveness for long-term treatments. The study provides new insights into these limitations and could help develop better methods for cell transformation in medical applications.
Hebrew University of Jerusalem is proud to announce that Professor Haitham Amal is among a large $17M grant consortium for pioneering autism research. This grant is part of an American funding initiative awarded by the California Institute for Regenerative Medicine (CIRM), aimed at advancing cutting-edge autism studies.
New study from Hebrew University reveals that marmoset monkeys use specific calls, known as "phee-calls," to name each other, a behavior previously known to exist only in humans, dolphins, and elephants. This discovery highlights the complexity of social communication in marmosets and suggests that their ability to vocally label each other may provide valuable insights into the evolution of human language.
In a groundbreaking discovery, researchers from Hebrew University have found that marmoset monkeys use specific vocal calls, called "phee-calls," to identify and communicate with each other. This ability to vocally label others has only been seen in humans, dolphins, and elephants until now.
Naming of others is a highly advanced cognitive ability observed in social animals and, until recently, was known to exist only in humans, dolphins, and elephants. Interestingly, our closest evolutionary relatives, nonhuman primates, appeared to lack this ability altogether.
In a new study published today in Science, a team of researchers from the Hebrew University, led by Dr. David Omer from the Safra Center for Brain Sciences (ELSC), made a groundbreaking discovery: for the first time, they found that marmoset monkeys use specific calls, called "phee-calls", to name each other.
To uncover this, the researchers, led by graduate student Guy Oren, recorded natural conversations between pairs of marmosets, as well as interactions between monkeys and a computer system. They found that these monkeys use their “phee-calls” to address specific individuals. Even more interestingly, the marmosets could discern when a call was directed at them and responded more accurately when it was.
“This discovery highlight the complexity of social communication among marmosets,” explains Omer. “These calls are not just used for self-localization, as previously thought— marmosets use these specific calls to label and address specific individuals”.
The study also revealed that family members within a marmoset group use similar vocal labels to address different individuals and employ similar sound features to code different names, resembling the use if names and dialects in humans. This learning appears to occur even among adult marmosets who are not related by blood, suggesting that they learn both vocal labels and dialect from other members of their family group.
The researchers believe that this vocal labeling may have evolved to help marmosets stay connected in their dense rainforest habitat,
where visibility is often limited. By using these calls, they can maintain their social bonds and keep the group cohesive.
“Marmosets live in small monogamous family groups and take care of their young together, much like humans do,” says Omer. “These similarities suggest that they faced comparable evolutionary social challenges to our early pre-linguistic ancestors, which might have led them to develop similar communicating methods.”
This research provide new insights into how social communication and human language might have evolved. The ability of marmosets to label each other with specific calls suggests they have developed complex brain mechanisms, potentially analogous to those that eventually gave rise to language in humans.
The study opens up exciting avenues for further research into how our own communication abilities may have evolved and what we can learn from these social nonhuman primates.
The research paper titled “Vocal Labeling of Others by Nonhuman Primates” is now available in Science and can be accessed at DOI: https://www.science.org/doi/10.1126/science.adp3757
Title: Barak | Credit: David Omer Lab
Title: Baby Bareket | Credit: David Omer Lab
Funding:
European Research Council (ERC—SYG—OxytocINspace) Grant Agreement: No. 101071777, OxytocINspace
Israel Science Foundation (ISF 915/22)
Researchers:
Guy Oren1, Avner Shapira1, Reuben Lifshitz1, Ehud Vinepinsky1, Roni Cohen1, Tomer Fried2, Guy P. Hadad2, David Omer1
Institutions:
The Hebrew University of Jerusalem is Israel’s premier academic and research institution. With over 23,000 students from 90 countries, it is a hub for advancing scientific knowledge and holds a significant role in Israel’s civilian scientific research output, accounting for nearly 40% of it and has registered over 11,000 patents. The university’s faculty and alumni have earned eight Nobel Prizes, two Turing Awards a Fields Medal, underscoring their contributions to ground-breaking discoveries. In the global arena, the Hebrew University ranks 81st according to the Shanghai Ranking. To learn more about the university’s academic programs, research initiatives, and achievements, visit the official website at http://new.huji.ac.il/en
New study reveals that giving internet users the choice to delay important security tasks, yet nudging them to commit to it later, makes them much more likely to complete these tasks. The study found that these nudges help people follow through without decreasing the rate at which they start the tasks right away. This offers a practical way to improve online security
In the face of rising cybersecurity threats, many internet users continue to neglect essential security actions, such as installing updates or changing compromised passwords. A new study led by Prof. Eyal Pe'er from the Federmann School of Public Policy at the Hebrew University of Jerusalem reveals that offering users the option to delay these tasks, combined with commitment nudges and reminders, significantly increases the likelihood of users eventually completing these important actions.
The research, conducted through a series of online experiments funded by a NSF-BSF grant to Prof. Peer and Dr. Serge Egeleman (U.C. Berkely), focused on understanding how these “nudges” could affect users’ willingness to change a compromised password. The findings are promising: when given the option to delay the task, a considerable number of participants chose to change their password later, resulting in a higher overall compliance rate without considerably reducing the number of users who opted to change their password immediately.
The study found that participants who made a promise to change their password later or requested a reminder were much more likely to follow through on their commitment. The effect was further enhanced when participants were reminded of their previous commitment, leading to a net positive impact on cybersecurity behavior.
"Security tasks often interrupt users at inconvenient times, leading to procrastination or outright neglect," explained Prof. Pe'er. "Our research shows that by allowing users to delay these and commit to completing them later, we can significantly increase the rate at which users complete critical security actions. This approach offers a practical behavioral solution to a common problem in online security."
The implications of this study are far-reaching, offering a simple yet effective strategy to improve cybersecurity compliance among internet users. By incorporating delay options and commitment nudges into security protocols, online platforms and services can better protect their users from potential security threats.
The research paper titled ““Protect Me Tomorrow”: Commitment Nudges to Remedy Compromised Passwords” is now available at ACM Journals and can be accessed at https://doi.org/10.1145/3689038.
Researchers: Eyal Pe'er1, Alisa Frik2, Conor Gilsenan3, Serge Egelman2,3
Institution:
The Hebrew University of Jerusalem is Israel’s premier academic and research institution. With over 23,000 students from 90 countries, it is a hub for advancing scientific knowledge and holds a significant role in Israel’s civilian scientific research output, accounting for nearly 40% of it and has registered over 11,000 patents. The university’s faculty and alumni have earned eight Nobel Prizes, two Turing Awards a Fields Medal, underscoring their contributions to ground-breaking discoveries. In the global arena, the Hebrew University ranks 81st according to the Shanghai Ranking. To learn more about the university’s academic programs, research initiatives, and achievements, visit the official website at http://new.huji.ac.il/en
A groundbreaking study demonstrates the first cost-effective method for producing cultivated meat. The study shows that continuous manufacturing addresses the key challenges of scalability and cost, potentially making cultivated meat accessible to everyday consumers and contributing to a more sustainable and ethical food system.
In an extraordinary stride for cellular agriculture, Professor Yaakov Nahmias, founder of Believer Meats, and a multidisciplinary team at the Hebrew University of Jerusalem and the cultivated meat industry unveiled a pioneering continuous manufacturing process for cultivated meat. This innovation tackles the industry's critical challenges of scalability and cost-effectiveness.
The study, "Continuous Manufacturing of Cultivated Meat: Empirical Economic Analysis," published in Nature Food, demonstrates the use of tangential flow filtration (TFF) for the continuous manufacturing of cultivated meat. The new bioreactor assembly permits biomass expansion to 130 billion cells per liter, achieving yields of 43% weight per volume. The process was carried out continuously over 20 days, enabling daily biomass harvests. Additionally, the research introduces an animal component-free culture medium, priced at just $0.63 per liter, which supports the long-term, high-density culture of chicken cells. In other words, this continuous manufacturing method could significantly reduce the cost and complexity of cultivated meat production, potentially bringing it closer to everyday consumers.
"We were inspired by how Ford’s automated assembly line revolutionized the car industry 110 years ago,” stated Prof. Nahmias. "Our findings show that continuous manufacturing enables cultivated meat production at a fraction of current costs, without resorting to genetic modification or mega-factories. This technology brings us closer to making cultivated meat a viable and sustainable alternative to traditional animal farming."
Bruce Friedrich, President of The Good Food Institute, expressed his support, stating, “GFI applauds the spirit of openness that continues to characterize cultivated meat researchers like Dr. Koby Nahmias and his colleagues, who understand that showing the scientific potential of cultivated meat will benefit all scientists working in the field.”
This research represents a significant advance in the economic feasibility of cultivated meat, addressing previous concerns about high costs and low yields. Utilizing this empirical data, the team conducted a techno-economic analysis of a hypothetical 50,000-liter production facility. The analysis indicates that the cost of production of cultivated chicken could theoretically be reduced to $6.20 per pound, aligning with the price of organic chicken.
Dr. Elliot Swartz, Principal Scientist at Cultivated Meat, The Good Food Institute emphasized the significance of the study’s findings, stating “This important study provides numerous data points that demonstrate the economic feasibility of cultivated meat. The study confirms early theoretical calculations that serum-free media can be produced at costs well below $1/L without forfeiting productivity, which is a key factor for cultivated meat achieving cost-competitiveness.” Dr. Swartz added that “Empirical data is the bedrock for any cost model of scaled cultivated meat production, and this study is the first to provide real-world empirical evidence for key factors that influence the cost of production, such as media cost, metabolic efficiency, and achievable yields in a scalable bioprocess design.”
While the authors acknowledged that various other factors would affect the final market price of cultivated meat, this research underscores the potential of continuous manufacturing to significantly lower production costs, making cultivated meat more accessible to consumers and competitive with conventional meat products.
This study not only highlights the promise of cellular agriculture in meeting the global demand for animal products but also aligns with broader environmental and ethical objectives by reducing reliance on traditional livestock farming.
The research represents the first demonstration of cost-efficient manufacturing of cultivated meat and the first empirical economic analysis based on solid data. It is a collaborative effort involving engineers, biologists, and chemists at the Hebrew University of Jerusalem and ADM-funded Believer Meats, which is currently building the world's first large-scale industrial production facility for cultivated chicken.
As global demand for animal protein is expected to double by 2050, cellular agriculture offers a solution to meet this demand, especially as resource-intensive livestock production reaches its peak capacity. Despite recent FDA approvals for cultivated meat production, large-scale production of cultivated meat has yet to become a reality. Previous techno-economic analyses suggested economic challenges, ranging from factory to raw materials costs, casting doubt about the viability of cultivated meat production.
This work presents groundbreaking solutions, including novel filter stack perfusion that reduced factory costs, an animal component-free medium that reduced raw material costs, and continuous manufacturing that increased factory capacity, projecting an annual production of 2.14 million kg of cultivated chicken at cost parity with USDA organic chicken even for a small 50,000-liter facility.
This technological advancement could have a profound impact on animal welfare, food safety, and food security, addressing the needs of a global population increasingly affected by climate change. The study is expected to generate significant interest across multiple disciplines and resonate in popular media due to its implications for the future of humanity.
The research paper titled “Continuous Manufacturing of Cultivated Meat: Empirical Economic Analysis” is available in Nature Food and can be accessed at https://www.nature.com/articles/s43016-024-01022-w
https://doi.org/10.1038/s43016-024-01022-w
Researchers:
Laura Pasitka1, Guy Wissotsky2, Muneef Ayyash1,2, Nir Yarza2, Gal Rosoff2, Revital Kaminker2, Yaakov Nahmias1,2,3
Institutions:
1) Grass Center for Bioengineering, The Hebrew University of Jerusalem
2) Believer Meats; Rehovot
3) Silberman Institute of Life Sciences, The Hebrew University of Jerusalem
The Hebrew University of Jerusalem is Israel’s premier academic and research institution. With over 23,000 students from 90 countries, it is a hub for advancing scientific knowledge and holds a significant role in Israel’s civilian scientific research output, accounting for nearly 40% of it and has registered over 11,000 patents. The university’s faculty and alumni have earned eight Nobel Prizes, two Turing Awards a Fields Medal, underscoring their contributions to ground-breaking discoveries. In the global arena, the Hebrew University ranks 86th according to the Shanghai Ranking. To learn more about the university’s academic programs, research initiatives, and achievements, visit the official website at http://new.huji.ac.il/en
