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DNA Evidence Triples Prosecution Rates in Criminal Cases, Reveals New Study in Israel

DNA Evidence Triples Prosecution Rates in Criminal Cases, Reveals New Study in Israel

16 July, 2023

A recent study conducted by the Hebrew University of Jerusalem sheds light on the impact of DNA profiles on prosecutorial decisions in the criminal justice system.

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In the pursuit of justice, law enforcement agencies heavily rely on forensic evidence, with DNA testing constituting the cornerstone of modern investigations. While the scientific and technological advancements in DNA testing have been extensively studied, there is scant evidence regarding how the availability of DNA evidence influences prosecutors’ decisions to move cases forward.

To address this knowledge gap, the research team created a unique database by combining data from the Forensics Division of the Israel Police, which documented the presence or absence of DNA profiles in criminal cases (n = 9862), with data on each case’s subsequent indictment decision from 2008 to 2019.

This extensive dataset’s analysis yielded significant insights into the impact of DNA evidence on criminal prosecutions. The researchers discovered that roughly 15% of all criminal cases presented to the prosecutor’s office were ultimately prosecuted. In stark contrast, the criminal justice system advanced approximately 55% of cases with DNA profiles. This effect demonstrates the significant influence DNA evidence has on the decisions of prosecutors.

The findings highlight the significance of using a scientific approach to prosecute offenders, recognising the value DNA evidence brings to the criminal justice system. However, the researchers caution against the indiscriminate use of DNA evidence and emphasise the necessity of prudence. DNA evidence is a potent tool, but it is not infallible; therefore, its use in the legal system must be carefully considered. The study encourages a balanced approach that harnesses the benefits of DNA evidence while acknowledging its limitations.

This research contributes to the ongoing dialogue surrounding the role of forensic evidence in criminal investigations, specifically highlighting the impact of DNA profiles on prosecution decisions in Israel. The findings have implications for law enforcement agencies, legal professionals, and policymakers involved in the pursuit of justice.

The study, titled “ The role of DNA in criminal indictments in Israel" was published in the Journal of Forensic Sciences - https://onlinelibrary.wiley.com/doi/pdf/10.1111/1556-4029.15327

The research team consisted of Esther Buchnik, Institute of Criminology, The Hebrew University of Jerusalem, Prof. Barak Ariel Institute of Criminology, University of Cambridge, Prof. Avi Domb Faculty of Medicine and the Institute of Criminology, The Hebrew University of Jerusalem, Nir Treves Faculty of Medicine, The Hebrew University of Jerusalem, Dr. Ron Gafny, Division of Identification and Forensic Science, Israel Police.

 

Methodology: The records examined were from 2008-2019. Over the study period, the average rate of indictment in all cases was approximately 15.1%, with a relatively stable variance [standard deviation (SD) of 0.8%]. However, 45.9% of criminal cases with DNA were subsequently indicted, with a steady yet clear increase over time (from 26.3% to 53.6% in 2019; SD = 11.8%).

The Hebrew University of Jerusalem is Israel’s premier academic and research institution. With over 23,000 students from 80 countries, it is a hub for advancing scientific knowledge and holds a significant role in Israel’s civilian scientific research output, accounting for nearly 40% of it and has received over 11,000 patents. The university’s faculty and alumni have earned eight Nobel Prizes and a Fields Medal, underscoring their contributions to ground-breaking discoveries. In the global arena, the Hebrew University ranks 77th according to the Shanghai Ranking, making it the top-ranked Israeli institution. To learn more about the university’s academic programs, research initiatives, and achievements, visit the official website at http://new.huji.ac.il/en

 

 

 

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New Hope for Inflammatory Disorders

New Hope for Inflammatory Disorders

19 July, 2023

New Hope for Inflammatory Disorders -
Controlling Dangerous Immune Response

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The inflammatory response is indispensable for protective immunity, yet microbial pathogens often trigger an excessive response, ‘cytokine storm’, harmful to the host. Despite recent advances in our understanding of inflammatory signaling, how to prevent a cytokine storm remains a challenge. A groundbreaking study has uncovered exciting possibilities for treating inflammatory disorders and preventing cytokine storms, which can be damaging to the body and even lethal. Scientists have discovered that: particular domains within key mediators of our immune response, called B7 and CD28 receptors, have a crucial role in enabling the inflammatory response and can be targeted with man-made molecules to manage immune responses and inflammation, saving lives. These findings bring us one step closer to developing effective treatments for inflammatory diseases.

 

A team of researchers at the Faculty of Medicine of the Hebrew University of Jerusalem, conducted this study with the aim of understanding how our immune system works and why it sometimes goes into overdrive during severe infections and autoimmune diseases. They created small copies of specific domains within the B7 and CD28 receptors, called mimetic peptides, to investigate how these affect the production of inflammatory molecules.

The study's results showed that these mimetic peptides successfully reduced the interaction between B7 and CD28 receptor proteins and thereby lowered the production of inflammatory molecules in human immune cells. This suggests that they could be used to develop treatments for inflammatory disorders, for example, in bacterial infections, in severe sepsis, and in viral infections involving lung injury such as influenza and corona.

Excitingly, when tested on mice, these mimetic peptides provided significant protection against lethal toxic shock caused by a harmful bacterial toxin that kills by eliciting an inflammatory cytokine storm. Even at exceedingly low doses, the specific B7-1 and CD28 mimetic peptides showed remarkable effectiveness in preventing the harmful effects of the toxin and protecting from death. "Our findings demonstrate for the first time the critical role played by these B7 and CD28 receptor domains in controlling immune responses and inflammation," said Prof. Raymond Kaempfer, of the Faculty of Medicine at the Hebrew University of Jerusalem. "By selectively reducing inflammation yet without completely stopping it, we may be able to protect against cytokine storms associated with severe infections and autoimmune diseases."

This research opens up new possibilities for developing targeted therapies that can balance immune activation needed to protect from pathogens yet prevent excessive inflammation. By regulating the interaction between B7 and CD28 receptors, we may be able to fine-tune the immune response and prevent harmful inflammatory reactions.

Funding: This work was supported by the US National Institute of Allergy and Infectious Diseases (NIAID) grants UC1AI067231 and 2U54AI057168, grant DM170164 from US Department of Defense Congressionally Directed Medical Research Programs (CDMRP) and the Milgrom Family Foundation to R. Kaempfer.

The research team consists of: Prof. Raymond Kaempfer, Dr. Andrey Popugailo, Dr. Ziv Rotfogel, Michal Levy, Orli Turgeman, Dalia Hillman, Dr. Revital Levy, Dr. Gila Arad, Dr. Tomer Shpilka – The Institute of Medical Research Israel-Canada at the Hebrew University-Hadassah Medical School.

Link to the publication: https://rdcu.be/dfCLm 

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Hebrew University Board of Governors: Eleven honorary doctorates awarded to inspirational researchers and leaders

Hebrew University Board of Governors: Eleven honorary doctorates awarded to inspirational researchers and leaders

13 June, 2023

yesterday, at the 86th convention of the Board of Governors, the Hebrew University awarded 11 honorary doctorates in recognition of the recipients’ contribution to science, society, and the Hebrew University.

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The doctorates were presented in the presence of senior figures from the public and business sectors, leading researchers at the University, the president of the Hebrew University, Prof. Asher Cohen, and the rector of the Hebrew University, Prof. Tamir Sheffer.

Prof. Asher Cohen, president of the Hebrew University, congratulated the awardees: “The Hebrew University is proud of the outstanding team of recipients of honorary doctorates for 2023. This team includes scientists, researchers, social and public figures, and leaders in their respective fields. Their academic excellence and contribution to the community and to society are an inspiration, and they serve as a model for academic flourishing and groundbreaking research.”

 

Prof. Jeffrey Ullman, Stanford W. Ascherman Professor of Engineering (Emeritus) at Stanford University—in recognition of his outstanding contribution to computer science research, and his commitment to the advancement of science.


Prof. Barbara Engelking , one of the pioneers of sociological research on the Holocaust, of the Institute of Philosophy and Sociology at the Polish Academy of Sciences—in recognition of her research of the testimonies of Polish Jews, establishing the Polish Center for Holocaust Research, and founding the only scientific journal in Poland about the Holocaust.


Mr. Arthur Gutterman—in recognition of his tireless dedication to Jewish communities around the world and his contribution to the security and prosperity of the State of Israel; his and his family's commitment to the teaching of the Holocaust in South Florida.


Prof. Sonia Livingstone OBE, professor of social psychology at the London School of Economics and Political Science— in recognition of her research into the impact of media policy in the United Kingdom, Europe, and internationally; of her efforts to enable children around the world to exercise their rights to safe access to the internet; and of her critical role in drafting the 25th amendment to the UN Convention on the Rights of the Child (UNCRC), relating to internet access.

Dr. Eric Steven Lander, of the Massachusetts Institute of Technology and Harvard University—in recognition of his contribution to the advancement of science around the world, particularly the mapping and sequencing of the human genome and the establishment of the Broad Institute, which offers a new and groundbreaking model based on collaboration and interdisciplinary efforts to address scientific challenges; and of the relationships he has fostered between the scientific communities in the United States and Israel.


Prof. Leon Mann AO, of the Department of Psychology at the University of Melbourne—in recognition of his groundbreaking research in the field of decision-making; of the translation of his academic findings into a curriculum that has formed part of the training for IDF officers and of other educational programs in Israel; and of his dedication to the Jewish people and the State of Israel, including the Hebrew University, where he founded the Phillip Mann Prize in memory of his late brother and the Mann Family Prize for Brain Science Research.


Mr. Yitzhak Manor—in recognition of his great contribution to strengthening trade relations between Israel and France, for which he received the highest civil honor in France and was sworn in to the Légion d’honneur; of his loyal service to the Hebrew University, where he served for nine years as a member of the Board of Directors and has now served for over a decade as a member of the Board of Governors; and of his generous contribution to the advancement of science at the University in a range of subjects.


Prof. Dr-Ing. Reimund Neugebauer, president of the Fraunhofer Society in Germany—in recognition of his outstanding academic career and founding the Fraunhofer Institute for Machine Tools and Forming Technology; and of his partnership with the Hebrew University, together with which he has chosen to establish two Fraunhofer research centers in Jerusalem, one for cybersecurity and the other for drug research.


Prof. Robert T. Knight, professor of psychology and brain science at the University of California in Berkeley and professor of neurology and neurosurgery at the University of California in San Francisco—in recognition of his outstanding academic achievements in cognitive brain science and in psychology; of his clinical work with patients and his efforts to make information accessible to the broader public, including by founding the journal Frontiers for Young Minds; and his role in ensuring the establishment of the Edmond and Lily Safra Center for Brain Sciences.


Mr. Yehoshua Sobol, one of the most important and outstanding artistic figures in Israel—in recognition of his storied career as a playwright, author, poet, and director, whose works provide a remarkable reflection of the Israeli experience; of his work to promote humanist values and social justice; and of his commitment to education, as manifested in his teaching at universities and colleges throughout the country, including the Hebrew University, where he devotes time to writing and to enriching the activities of the University’s Israel Institute for Advanced Studies.


Dr. Raymond F. Schinazi, of the Emory University School of Medicine—in recognition of his medical research, which has affected the lives of millions of people through the discovery of effective medicines for diseases that were previously considered untreatable; of his commitment to making medicines available to people in the country of his birth, Egypt, from which he fled as a boy, and in Georgia; and of his involvement in training the next generations of medical researchers via the initiative he founded with the Hebrew University and Hadassah School of Medicine.


The Samuel Rothberg Prize for Jewish Education was awarded to Rabbi Dr. Benjamin (Benny) Lau, one of the most prominent figures in Israeli society today, who has dedicated his life to making Judaism more accessible to the wider Israeli public in various ways. Rabbi Dr. Lau is one of the most outspoken voices calling for the institution of the rabbinate to be adapted to modern times, including by updating ceremonies in the Jewish life cycle such as marriage and conversion, as well as the participation of women in religious worship.

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Einstein House at the Hebrew University

Einstein House at the Hebrew University

14 June, 2023

The President of Israel, the President of the Hebrew University, the Mayor of Jerusalem, and art art collecter Jose Mugrabi
laid the cornerstone of a house to display Einstein’s legacy

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President Isaac Herzog of Israel, Hebrew University President Prof. Asher Cohen, Jerusalem Mayor Moshe Leon, and Mr. Jose Mugrabi, a prominent art collector, laid the cornerstone for Einstein House, at the Hebrew University’s Edmond J. Safra campus, on Givat Ram, in Jerusalem.

The Einstein House will house exhibits of the legacy, work, and research of Nobel laureate Albert Einstein, one of the founders of the Hebrew University, who bequeathed all his writings and intellectual property to it. The House will serve as a center for scientific and technological education and employ modern display techniques, scientific demonstrations, and original documents to showcase Einstein’s immense contribution to science. The distinctive building, designed by the world-renowned architect Daniel Libeskind, will highlight the impact of Einstein's discoveries, his involvement in humanitarian and civil rights issues, as well as his deep commitment to Hebrew University, the State of Israel, and the global Jewish community. The public will be able to tour a reconstructions of his personal library, his office, and view original documents, including on the general theory of relativity and the manuscript containing the famous equation E=mc².

 

President Isaac Herzog said that ‏“It is a great pleasure to be addressing you here at ‏the Board of Governors meeting at this great Israeli institution, the Hebrew University of Jerusalem. ‏I am especially excited to be here to lay the cornerstone for Einstein’s House. Right here, we are laying the foundations for a vital living archive of the writings of one of the greatest minds in the history of humanity.

But we are also laying the foundations for a beautiful building designed by the architect Daniel Libeskind, for a legacy that goes far beyond any one person alone: This is the legacy of human curiosity – ‘holy curiosity’ as Einstein himself put it.
Over the past century The Hebrew university has blossomed into a world-class institution that is at the forefront of global research and of contribution. I thank the government of Israel and other partners in this wonderful project, for moving this project and initiative so that we can realize it hopefully in two years’ time when we will celebrate 100 years to the founding of the university.”

At the ceremony, Hebrew University president Prof. Asher Cohen observed that the “Einstein House will provide the general public with a look at the science of the man who sketched out the path for us and who, a century later, continues to serve us as a model of scientific excellence day after day. Our task is first and foremost to practice science and produce breakthroughs that will improve the life of all humanity; but a no less important part of this task is to explain science and make it make accessible to large audiences. This is precisely the vision behind the Einstein House.”

Jerusalem Mayor Moshe Lion: "The Einstein House will be established here, in this place, as a living monument, to the ideal of academic excellence, to the value of exploring, discovering, and learning more about the world around us. The Einstein House will be a house of learning, and a house of teaching. A house where everyone who enters, will leave richer in knowledge, with a better understanding of the past, and greater hope for the future. I want to congratulate all the partners in this amazing project. I have no doubt it will make a significant contribution to the city and to the students."

Jose Mugrabi, philanthropist and art collector: “We look forward to seeing the wonders that this House will bring to Israel and the rest of the world in the future. The Einstein House represents so much more than the physical space. It will be a center of science and technology for our students, and we are convinced that this place will create a new generation of Einsteins.

I am so excited to be here tonight and to be associated with Albert Einstein. In my past I didn’t study practically at all, and tonight to be associated with the genius of the century – I have no words. I feel like the luckiest man in the world.”

 

 

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Israeli astrophysicists may have solved the mystery of early massive galaxies

Israeli astrophysicists may have solved the mystery of early massive galaxies

1 June, 2023

A new theoretical model made by Israeli astrophysicists reveals an excess of massive galaxies, in contrast to previously accepted theories.

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The mystery of the formation of early massive galaxies in the universe has finally been solved by astrophysicists from the Hebrew University of Jerusalem (HU) who have published a new theoretical model that explains recent observations that used NASA's James Webb Space Telescope (JWST).

They said they revealed a surprising excess of massive galaxies in the universe – already in the first half billion years after the Big Bang – contrary to the commonly accepted theory.

The team published their findings in Monthly Notices of the Royal Astronomical Society under the title “Efficient formation of massive galaxies at cosmic dawn by feedback-free starbursts.”  

 

 

Researchers discover excess of massive galaxies

The James Webb telescope was launched into space at the end of 2021 and started producing images of distant galaxies as early as last July. The researchers unexpectedly discovered an excess of massive galaxies in the early universe compared to the number of galaxies expected according to the common theory.

According to the researchers’ proposed model, the special conditions that prevailed in the primordial galaxies, of high density and low abundance of heavy elements, allowed the formation of stars with high efficiency without interference from other stars. 

The research team from HU’s was led by Prof. Avishai Dekel with Dr. Kartick Sarkar, Prof.  Yuval Birnboim, Dr. Nir Mandelker and Dr. Zhaozhou Li. The Racah Institute of Physics, located on the university’s Safra Campus (Givat Ram) campus, has some 90 faculty members who teach and carry out research in the fields of astrophysics, condensed matter physics, high energy physics, bio and non-linear physics, nuclear physics, and atomic, molecular and optical physics.

“Already in the first half-billion years, researchers identified galaxies that each contain about ten billion stars like our Sun,” Dekel explained. “This discovery surprised researchers who tried to identify plausible explanations for the puzzle, ranging from the possibility that the observational estimate of the number of stars in galaxies is exaggerated, to suggesting the need for critical changes in the standard cosmological model of the Big Bang.”

 

According to the prevailing theory of galaxy formation, gravity causes gas scattered in the universe to collapse into the centers of giant spherical clouds of dark matter, where it becomes luminous stars, like the Sun. But theory and observations until now have shown that the efficiency of star formation in galaxies is low, with only about 10% of the gas that falls into the clouds becoming stars.

The inefficiency is caused by remaining gas heating up or being blown out of galaxies under the influence of winds and supernova explosions from the stars that manage to form first. This contradicts recent JWST indications of vast amounts of stars created in a short time frame, he continued. 

Is this the key to explaining super-massive black holes?

In this study, Dekel and his team proposed a process termed “feedback-free starburst” (FFB), which naturally explains the mystery. Under the unique conditions prevalent in early galaxies, gas efficiently turns into stars without being disrupted by feedback processes.

This idea is based on a time delay of more than a million years between the formation of massive stars and their subsequent explosions as supernovae.

Before the enrichment of the gas by heavy elements produced in stars, the researchers suggest star-forming clouds in the dense early universe had a density above a threshold that allowed the rapid collapse of the gas into stars within the “window of opportunity” of one million years. This process of high-efficiency star formation in the absence of feedback explains the observed excess of massive galaxies.

“The publication of this research marks an important step forward in our understanding of the formation of primordial massive galaxies in the universe and will no doubt spark further research and discovery,” Dekel concluded.

“The predictions of this model will be tested using the accumulating new observations from the Web Space Telescope, where it seems that some of these predictions are already confirmed. Important implications of the proposed FFB scenario will be investigated in future studies.

These include the efficient formation of seed black holes of a thousand solar masses in the centers of the FFB star-forming clusters, which are key to explaining the surprisingly supermassive black holes of a billion solar masses seen in centers of galaxies half a billion years later.”

 

 

 

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Hebrew University’s Asper Prize Startup Award 2023, Avertto

Hebrew University’s Asper Prize Startup Award 2023, Avertto

12 June, 2023

(L-R) Anita Wortzman, Gail Asper, Dr. Hila Ben-Pazi, Prof. Asher Cohen, Yaniv Kirma, Ayelet Cohen, Dr. Amnon Dekel, Shira Gershuni – (photo credit: BRUNO SHARVIT)

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45 starts ups competed leading to a shortlist of 5 hoping to win the 100,000 Shekel prize. The winner, Avertto, developed a device and monitoring system which creates an alert in the event of imminence of stroke.

Click here to read more.

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Archaeologists discover and replicate earliest musical instrument in the Middle East

Archaeologists discover and replicate earliest musical instrument in the Middle East

9 June, 2023

Archaeologists are hearing for the first time how humans made music some 12,000 years ago, by recreating a flute that was likely used to hunt ducks and other small birds in northern Israel.

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On Friday, a team of Israeli and French researchers published an article about the recreated bone flute in the peer-reviewed Nature Scientific Report, offering an auditory window into how early humans shifted from hunter-gatherers to more settled villages, creating the earliest known musical instruments ever discovered in the Middle East.

The French-Israeli team of archaeologists discovered fragments of seven different flutes, dating to around 10,000 BCE, which is the largest collection of prehistoric sound-producing instruments ever found in the Levant. The pieces were found at the Eynan/Ain Mallaha site, a small village some 35 km (20 miles) north of the Sea of Galilee. The site was inhabited from 12,000 BCE to 8,000 BCE, around the time when humans were undergoing a massive revolution from nomadic hunter-gatherers to more sedentary, semi-settled communities.

 

Dr. Laurent Davin, a post-doctoral fellow at Hebrew University, was examining some of the bones recovered from the site when he noticed tiny holes drilled at regular intervals along a few of the bones. At first, experts had dismissed the holes as regular wear and tear on the delicate bird bones. But Davin examined the bones more closely and noticed that the holes were at very even intervals, and clearly created by humans.

“One of the flutes was discovered complete, and so far as is known it is the only one in the world in this state of preservation,” Davin said in a press release that accompanied the article’s publication.

 

Dr. Hamoudi Khalaily, a senior researcher with the IAA, spent 10 years excavating at the Eynan site and was instrumental in creating a replica of the extant flute.

“There were a lot of doubts that this was even possible [to recreate], but the replica was created exactly [in the same way] as the original and it allowed us to hear what people would have heard 12,000 years ago,” Khalaily told The Times of Israel.

“When we first heard it, it gave us this feeling like, we are really doing something for history,” Khalaily said.

 

The recreated flute produces a screeching, breathy whistling sound that Khalaily and the team believe could be an imitation of predator birds, including falcons, which eat small waterfowl.

“The sound could have attracted predator birds, which creates chaos with the other birds, and then it’s very easy to catch them, even with your hands,” explained Khalaily.

Previously, nomadic hunter-gathers had focused on bigger game such as gazelles, rabbits, or foxes. But when humans began settling in the Hula Valley for the first time, they started taking advantage of new food sources, including fish and smaller waterfowl in the lake that used to stretch across the Hula Valley.

Today, the Hula Valley is still a major conduit for bird migration in the late fall when tens of thousands of birds pass through Israel on their way from Europe to Africa. The Hula Valley was once covered by water, with a 13 square kilometer (5 square mile) lake and 47 square kilometers (18 square miles) of seasonal swamps. Early Zionist pioneers drained the swamp in the early 20th century as a major infrastructure project to create more agricultural land and to combat malaria.

 

A trove of bird bones

At the Eynan site, archaeologists are excavating a small Natufian village, which was a Mesolithic culture in the Levant and Western Asia around 9000 BCE. It’s a unique time because the culture emerged when humans started living a semi-sedentary lifestyle predating the agricultural revolution, meaning they had to find regular food sources in the same area even before they knew how to cultivate them. Once humans became more settled, their culture underwent dramatic societal change including the appearance of burial practices, art, and durable structures.

 

The Eynan site was first excavated by a French mission in 1955 and later from 1996–2005 by a joint team from Israel and France directed by François Valla of the Centre Nationale de Recherche Scientifique (CNRS) and Khalaily of the Israel Antiquities Authority.

Excavations at the site are ongoing and it can take years to methodically sift through all of the earth removed from a site and search for fragments of tools, animal bones, or other detritus from daily life thousands of years ago. Over the past two decades, careful sifting has yielded 1,112 bird bones from the Eynan site.

 

The bone flute was researched and recreated by a team of French and Israeli experts, consisting of archaeologists and archaeozoologists, who study animal bones, ethnomusicologists, paleo-organologists (the research of ancient sound-making instruments), and technical experts that were able to find ways to recreate the exact placement of the finger holes.

The original flutes, also called aerophones because they are an instrument that produces sound due to vibrating air, were made from the hollow wing bones of the Eurasian teal and the Eurasian coot. The current replica was made from the wing bones of two female mallard ducks “because of the difficulty in obtaining carcasses of Eurasian coot (Fulica atra) used by the Natufians,” the article stated.

The tinier the bone, the more difficult it is to play. The researchers believe the bones were chosen specifically to mimic the calls of the Eurasian Sparrowhawk and the Common Kestrel, two birds of prey that were widespread in the Hula Valley.

 

The flute represents the oldest musical instrument found locally, but it is not the oldest aerophone that has been discovered. Most of the known Paleolithic sound-making instruments are found in Europe, and the oldest dates to around 40,000 years ago, which was found in southwestern Germany, made from bird bone and mammoth ivory.

Previous to this discovery, the only known “music” or sound production during the Paleolithic and Neolithic periods in the Levant was from a few studies suggesting that humans could have developed a belt of bone pendants that clacked and rattled, or possibly a bone whistle (flute with no fingerholes).

The flute represents an important discovery, but it’s not music to everyone’s ears. 

“I heard it for the first time on Youtube, and it’s really a terrible tone, it’s high and pitchy and not nice at all to my ear,” said Prof. Rivka Rabinovich, the scientific director of archeozoological collections at the National Natural History Collections at the Hebrew University. Rabinovich, an expert in studying and interpreting the remains of ancient mammal bones has been studying the discoveries from the Eynan site for years.

Rabinovich added that there’s no way of knowing whether ancient humans had a similar cringe reaction when they heard it; whether it was used for hunting, communication, or making music.

But it opens a window into a fascinating point in human development, the complexity of society and their ability to make tools. The small finger holes in the flute were drilled with the talon of a larger bird, likely a falcon. Archaeologists believe that talons also had spiritual significance to early humans, Khalaily said.

 

“It’s very interesting because this is just at the starting point of people becoming more sedentary,” Rabinovich said. “It’s a very exciting period at which to understand the day-to-day life and also larger questions beyond day-to-day life, and why they did certain things.”

She credited the discovery to the large and varied French-Israeli team, which united researchers and archaeologists with areas of expertise in niche areas like reconstructing bone tools and interpreting scratches made in animal bones.

“The message from this is that you really need to save everything [excavated from a site] because you always see these things with new eyes and new tools,” she said. “It takes a long time to sift through things, and when you look at it anew, you can see it differently. That’s because there’s continually new research, there’s continually new technology, and new ways to investigate new information. And it all works together to create a more complete picture of what happened there.”

 

The Eynan site hosted continuous human presence for around 4,000 years, with people living in round houses made of stones with animal hides or branches for roofs. In 8,000 BCE, when the agricultural revolution was well underway, humans abandoned the site, moving around 500 meters closer to the Hula Lake, whose contours had changed with time.

One of the most important tests on the flute is yet to come: In late fall, when the annual bird migration through the Hula Valley takes place, Khalaily plans to take the replicated flute to the Eynan site and play it there, in the same spot where humans created it 12,000 years ago.

“I want to go and see if we can make these voices, in hopes of attracting a hawk or falcon,” he said. “I’m naturally an optimistic person, but I do really think it will work. If we were able to replicate this sound, I’m certain it will bring those birds to us.”

This artical is from The Times of Israel

 

 

 

 

 

 

 

 

 

 

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Hebrew wasn’t spoken for 2,000 years. Here’s how it was revived

Hebrew wasn’t spoken for 2,000 years. Here’s how it was revived

11 May, 2023

Hebrew wasn’t spoken for 2,000 years. How was it revived? Meirav Reuveny, a Hebrew language historian at The Hebrew University of Jerusalem, explains some of the history behind how a language once thought to exist only in ancient religious texts, is now spoken by millions.

Story by Allie Yang

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Today, Hebrew is a thriving language—used by millions of speakers around the world to communicate all their thoughts and desires. 

That may have seemed almost impossible less than 150 years ago, when the language was thought to exist only in ancient religious texts. For some two thousand years, Hebrew laid dormant as Jewish communities scattered across the globe, and adopted the languages of their new homes. By the late 1800s, Hebrew vocabulary was limited to archaic and religious concepts of the Hebrew Bible—and lacked words for everything from “newspaper” and “academia” to “muffin” and “car.”

 

Here’s a look at the bumpy road to modernizing Hebrew and the debates that surround its continuing evolution today.

Hebrew never really died

The Jewish people were once known as Hebrews for their language, which flourished from roughly the 13th to second centuries B.C.—when the Hebrew Bible, also known as the Old Testament, was collected. Hebrew was used in daily life until the second century B.C. at latest, experts believe.

 

But beginning in the second century B.C., Jewish people became increasingly ostracized and oppressed. Through the rise and fall of Rome, the Middle Ages, Renaissance, and beyond, they were forced to migrate around Europe and adopted the language of the country they were in. They also formed new languages like Yiddish, which mixed Hebrew, German, and Slavic languages.

Still, the Jewish people were known as “People of the Book.” As part of traditions like studying the Torah and reading it aloud, Jews continued to learn Hebrew to read from the Bible and written Hebrew lived on for more than a millennium mostly through religious practice.

There were exceptions: more educated Jews exchanged messages in Hebrew, sometimes between merchants for records of business, says Meirav Reuveny, a Hebrew language historian at the Hebrew University of Jerusalem. A 10th-century trove of documents showed that some women, a group generally confined to domestic duties at the time, also wrote letters, exchanged legal documents, and recorded business in Hebrew. From the 10th to 14th centuries, there was an explosion of secular Hebrew poetry in Andalusia, Spain.

Waking the giant

In the 19th century, most Jews in Europe were still second-class citizens when a new movement emerged that looked to Hebrew as a way to inspire hope through the Jewish people’s glorious past, Reuveny says. Hebrew revivalists wanted to expand the language beyond the abstract concepts in the Bible—they wanted to use it to talk about modern events, politics, philosophy, and medicine. 

Among the leaders of the movement was Eliezer Ben-Yehuda, credited as the father of Modern Hebrew.

“One person cannot invent a language,” Reuveny says. “But he makes a good hero, something important for a social movement.”

Ben-Yehuda was born in 1858 in Lithuania, where Jews were heavily discriminated against and violent pogroms terrorized Jewish communities regularly. When Ben-Yehuda traveled to Paris in 1878, he was empowered by the growing Jewish nationalist movement he witnessed there.

He believed Jews needed a country and language to flourish. He moved to Jerusalem in 1881, where he and his wife made the decision to only speak Hebrew—despite missing words for essential modern items and concepts. They raised their son Itamar Ben-Avi to be the first native Hebrew speaker in almost 2,000 years.

In the beginning, Hebrew went through growing pains: the language needed many new words. Ben-Yehuda made a dictionary of new Hebrew words (including מילון, or milon, the word for dictionary). Hebrew newspapers across Europe invented their own words, too, Reuveny says.

Many people saw this as an unwelcome change—swapping an ancient and sacred language to a new and strange one. Hebrew revivalists chose a difficult way of life by speaking only Hebrew, before it could meet the needs of modern life.

Gradually, the language was standardized in the early 20th century. The first Modern Hebrew dictionary was released in its completed form in 1922. Hebrew language schools were opened, then Hebrew became the language of instruction of all subjects in Jerusalem schools (the first in 1913). 

After the state of Israel was established in 1948, people flocked from all over the world. Many young adults learned Hebrew through the young nation’s mandatory military service, though most families in Israel became Hebrew speakers over one to two generations.

Today, of the 9.5 million people in Israel aged 20 and over, almost everyone uses Hebrew, and 55 percent speak it as their native language. Around the world there are around 15 million Hebrew speakers; in the U.S., there are 195,375.

An unstoppable force

Modern Hebrew has changed significantly but still shares clear ties with Biblical Hebrew. 

King David and I could probably understand each other,” says Mirit Bessire, Hebrew language program director at Johns Hopkins University, who points out that it’s not all that different from modern English speakers attempting to understand someone using Shakespearean English.

The growing pains Hebrew experienced as it modernized during Ben-Yehuda’s time are echoed in controversies today. Inclusive language such as non-binary adaptations have proven difficult to adopt as Hebrew is significantly gendered, Reuveny says. Modern words and concepts like “gaslighting” also stir debate about how much outside cultures are affecting the language.

“Language does naturally evolve and grow. It’s inevitable. It’s not in our hands what our language does,” Bessire says. 

Language fills the needs of its users, she adds—and today we have more needs than ever as social media and email connect communities of Hebrew speakers far beyond Israel. For example, Bessire says, there are Hebrew communities in China that are not Jewish but have become fluent in the language for business purposes.

“Hebrew is a language of proficiency,” Bessire says. “It's a language that you use for your everyday life, from technology to medicine.”

From The National Geographic

 

 

 

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An Astronaut Visitor to HU’s Ein Kerem Campus

An Astronaut Visitor to HU’s Ein Kerem Campus

2 April, 2023

 

On March 21, Eytan Stibbe, a member of the University’s Board of Governors, an Honorary Fellow and the second Israeli to travel to outer space, visited the Ein Kerem campus as part of the Rakia Mission to Send the Second Israeli to Space (in which Eytan participated).

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He met with President Prof Asher Cohen, VP of R&D Prof Aharon Palmon, dean of the Faculty of Medicine, Prof Dina Ben-Yehuda, dean of Pharmacy, Prof Sara Eyal, and a with Dr Deganit Paikowsky, a lecturer in the department of international relations and until recently the vice president of the International Astronautical Federation.

He later met with researchers at the Faculty of Medicine, who shared potential experiments for outer space, as well as with inspirational students.

Lastly, Mr Stibbe delivered a fascinating lecture on his space mission to an audience of 100+ people. He was very impressed with the research and students’ curiosity.

 

 

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A Sabaean Inscription on a Large Clay Jar Deciphered and Discovered Less Than 300 Meters from the Site of the Jerusalem Temple

A Sabaean Inscription on a Large Clay Jar Deciphered and Discovered Less Than 300 Meters from the Site of the Jerusalem Temple

3 April, 2023

In a new study [SJ1] published in Hebrew University’s Jerusalem Journal of Archaeology, Dr. Daniel Vainstub deciphered a partially preserved inscription that was found on the neck of a large jar dated back to the time of King Solomon.

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The jar was originally discovered together with the remains of six other large jars during excavations carried out in 2012 in the Ophel area south of the Temple Mt., led by the late Dr. Eilat Mazar from the Institute of Archeology of the Hebrew University of Jerusalem. From the original inscription, only seven letters survived. Over the course of the last decade, more than ten researchers suggested various readings without reaching a consensus, but they agreed the inscription is written in Canaanite script, from which the ancient Hebrew script that used during the time of the First Temple, was developed. In the study, Dr. Daniel Vainstub determined the script is "Ancient South Arabian," the script that was used in the south-west part of the Arabian Peninsula (the Yemen region of today), where the Kingdom of Sheba was the dominant kingdom at that time.

Dr. Vainstub explains, "Deciphering the inscription on this jar teaches us not only about the presence of a speaker of Sabaean in Israel during the time of King Solomon, but also about the geopolitical relations system in our region at that time - especially in light of the place where the jar was discovered, an area known for also being the administrative center during the days of King Solomon. This is another testament to the extensive trade and cultural ties that existed between Israel under King Solomon and the Kingdom of Sheba."

According to the new interpretation, the inscription on the jar reads, "[ ]shy l'dn 5," means five " šǝḥēlet," referring to one of the four ingredients mentioned in the Bible (Exodus 30:34) required for the incense mixture. The " šǝḥēlet " was an essential ingredient in the incense that was burnt in the First and Second Temples and was called "tziporen" in Rabbinic literature. This indicates a clear connection between Jerusalem of the 10th century BCE (the days of the Kingdom of Solomon) and the Kingdom of Sheba. It appears that the pottery jar was produced around Jerusalem and the inscription on it was engraved before it was sent for firing by a speaker of Sabaean who was involved in supplying the incense spices.

The Ophel site in the Archaeological Park at the foot of the southern wall, within the area of the Jerusalem Walls National Park, includes a trail that passes between 2,000-year-old mikvahs used by pilgrims to the Temple. This is also the area where an administrative center of the kingdom of King Solomon was located.

During the 10th century BCE, the Kingdom of Sheba thrived as a result of the cultivation and marketing of perfume and incense plants, with Ma'rib as its capital. They developed advanced irrigation methods for the fields growing the plants used to make perfumes and incense. Their language was a South Semitic one. King Solomon is described in the Bible as controlling the trade routes in the Negev, which Sabaean camel caravans carrying perfumes and incense plants passed through on their way to Mediterranean ports for export.

The initial excavation led by Dr. Eilat Mazar was funded by Daniel Mintz and Meredith Berkman of New York, with assistance from Herbert W. Armstrong College in Oklahoma, USA, and the East Jerusalem Development Company.

 

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HU Researchers Develop New Method to Prevent Mosquito Bites

HU Researchers Develop New Method to Prevent Mosquito Bites

18 April, 2023

Researchers at HU have developed a safe new method of preventing mosquito bites using a skin coating from naturally occurring cellulose nanocrystals (CNCs).

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According to a study published in PNAS NEXUS, applying the thin CNC coating on human skin decreases the number of mosquitoes feeding by 80%. Cellulose CNCs are a renewable raw material produced from wood, cotton or other cellulose-rich sources and are used in cosmetics, composites, food packaging and medical devices.

To read the full story visit JNS.org.

 

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Researchers Develop New Drought Tolerant Variety of Tomatoes

Researchers Develop New Drought Tolerant Variety of Tomatoes

19 April, 2023

 

Researchers at the Hebrew University of Jerusalem (HU) succeeded in developing tomato varieties that require less water and produce a high yield, even in extreme drought conditions

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The study, published in the Proceedings of the National Academy of Sciences (PNAS) journal was led by doctoral student Shai Torgeman and Prof. Dani Zamir from the Hebrew University Robert H. Smith Faculty of Agriculture, Food, and Environment.

 

The researchers identified interactions between two regions of the tomato genome that resulted in a 20-50% increase in the overall tomato yield under irrigated conditions as well as in droughts.

“The unique structure of the new population, which enables precise mapping of the tomato genes, has the potential for extensive application in other plants and could increase productivity,” the researchers say.

Tomatoes grown in open field conditions need protection from pests and fertilization and must be watered over time. However, the climate crisis and the severe water shortages around the world require alternative varieties and new cultivation methods that also guarantee adequate profits for farmers.

 

The researchers crossbred two tomato species – a wild tomato from the deserts of western Peru and the cultivated tomato – to identify which regions of the genome affect important agricultural traits, such as yields. Individually, one genome didn’t affect the crop, but when these genome regions appeared together, there was a significant contribution to fertility even in dry conditions.

“Studies of complex traits in plants, such as yield and resistance to drought conditions, have been based on significantly smaller populations of 200~ species,” explained Torgeman. “This makes it impossible to identify all the interactions (epistasis) between the genes, as well as their influence on important agricultural traits. In this study, we genetically crossed two different species of tomato, and proved that by using a larger population and a genetic map that includes thousands of markers, it is possible to identify areas in the genome that have interaction between them that increases the yield.”

 

 

“Studies of complex traits in plants, such as yield and resistance to drought conditions, have been based on significantly smaller populations of 200~ species,” says Torgeman. “This makes it impossible to identify all the interactions (epistasis) between the genes, as well as their influence on important agricultural traits. In this study, we genetically crossed two different species of tomato, and proved that by using of a larger population and a genetic map that includes thousands of markers, it is possible to identify interactions that increase the yield.”

Zamir’s lab has conducted DNA sequencing and extensive data analysis of 1,400 plants over the past four years. The researchers are seeking to commercialize these new tomato varieties.

 

“With global warming and farmers need tomatoes that can cope with these changing weather conditions,” Torgeman says. “Global warming does not only cause higher temperatures but also extreme weather like sudden torrential downpours or drought, so we need plants that have improved capabilities.”

The research was conducted as part of the scientific cooperation with the European Union in the ‘Horizon 2020’ program.

 

 

To read the full story visit The Jerusalem Post.

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French dairy giant Danone leads $3.5m investment into Israeli cultured milk startup

French dairy giant Danone leads $3.5m investment into Israeli cultured milk startup

4 April, 2023

Strategic investment by company’s venture arm includes potential collaboration on cultured breast milk products; other investors include Steakholder Foods and Coca-Cola Israel

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French dairy giant Danone has entered into a strategic investment agreement with Israeli startup Wilk, which could lead to a collaboration with the food tech firm to develop cultured breast milk components for infant formula based on its cell technology.

Danone Manifesto Ventures (DMV), the corporate venture arm set up by the Paris-based food giant, will invest $2 million, leading a $3.5 million financing round announced by Wilk, in a filing to the Tel Aviv Stock Exchange on Monday.

Following the investment, the venture arm of the dairy company, which makes Activia yogurt, Aptamil infant formula and Evian water, will hold at least 2% of Wilk’s share capital.

 

Dr. Nurit Argov-Argaman of the Hebrew University of Jerusalem founded Wilk (as Biomilk) in 2018, and has since developed cell-based technology to produce cultured human breast and animal milk. Argov-Argaman took it public on the TASE in 2021 in a SPAC (special-purpose acquisition company) merger deal.

For the animal-derived cultured milk, Wilk isolates the milk-producing cells from cows’ udders and transfers them to a bioreactor, where they are exposed to materials patented by the firm to produce milk ingredients, but without needing a cow in the final milk-producing process.

 

The process is also applied to the lab production of human breast milk — complete with the fats and proteins that make up important parts of the nutritional value — using cells from breast reduction surgeries.

As part of the strategic agreement between Danone’s venture arm and Wilk, the parties will examine strategic cooperation for the development of breast milk substitutes that will include lab-grown breast milk components.

The agreement also stipulates that Danone and Wilk will examine possibilities for joint commercial cooperation and operations, which may include agreements for joint development and grants for projects in Europe and the US, Wilk said in a statement.

 

Wilk CEO Tomer Aizen said that DMV’s investment will help the firm continue in the development of its cultivated milk products.

Wilk is one of several Israeli food tech companies developing cultured, animal-free milk, each at a different development stage. Rehovot-based Remilk, for example, last year raised $120 million for cow-free milk, cheese and yogurt, and with production capabilities already off the ground. The developer of cultured milk and dairy has also announced plans to open the “world’s largest” facility for the production of cow-free milk in Denmark.

However, Wilk is one of few companies on the world stage in the cultured breast milk sector. Wilk’s offering could be a welcome alternative for those who prefer to give human milk, but face difficulties breastfeeding, for babies born prematurely, and for those who cannot consume commercial infant formula.

Wilk said it is not necessarily looking to replace infant formula, but to contribute to a product that is better nutritionally and with a cost comparable to formula.

As such, the Rehovot-based startup has been focusing on developing cell-cultured human milk fat for infant formula to replace vegetable fats currently contained in formula. The nutritional benefits of cultured human milk fat play a central role in maintaining an infant’s digestive system, as well as the development of its brain and nervous system, according to Wilk.

Other investors in the latest funding round, include Rehovot-based Steakholder Foods (formerly Meatech), an Israeli maker of cultivated meat products, which will purchase $450,000 in ordinary shares of Wilk at a 15% discount below their 45-day average closing price, giving the company a 2.5% stake in the Israeli startup. Steakholder Foods said it seeks synergies with Wilk, including strategic cooperation on its proprietary biology and printing technologies.

 

The Central Bottling Company, also known as Coca-Cola Israel, is also participating in the funding round. The owner of the Tara dairy cooperative, Israel’s second-largest milk processing company, invested $2 million in Wilk back in 2021 as part of an agreement to develop products based on the startup’s cultured milk technology.

As part of the financing round, Wilk will issue a total of 13.6 million ordinary shares in a private placement at a price of NIS 0.91 per share. The startup’s shares closed 10% lower on Monday at NIS 105.1 per share.

 

from: The Times of Israel

 

 

 

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Face to Face with Prof. Yuval Noah Harari

Face to Face with Prof. Yuval Noah Harari

17 April, 2023

Prof. Yuval Noah Harari – Hebrew University lecturer, historian, philosopher, and author of Sapiens, one of the 21st century’s most influential books – joins the Dean of Humanities, Prof. Nissim Otmazgin, for a thought-provoking conversation on the challenges faced by higher education, the skills graduates will need for tomorrow’s global job market, and what role the humanities will play in the 21st century.

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Otmazgin: Welcome, Yuval, it’s a pleasure to have the opportunity to interview such a distinguished member of our faculty. Many thanks for joining us today.

Harari: It’s an honor, Nissim. As you know, The Hebrew University of Jerusalem has been my home for most of my life, since the age of 17 when I first began my BA studies in history. I’m thrilled to be here.

Otmazgin: Yuval, what do you think is the greatest challenge faced by institutions of higher education today?

Harari: I think that the challenge I’m most concerned about is the politicization of science – the manner in which scientific theories and debates have rapidly become political debates – and how it creates new threats to our academic freedom and our freedom of speech.

We see this trend in history departments all over the world. Many politicians feel that history is much too important to be left to the historians, and politicians frequently distort historical evidence in the name of ideology. This, of course, isn’t new. History has always been a political subject, and has always struggled with censorship and political repression by those who dislike what historians have to say.

Otmazgin: Would you say that this challenge is limited to historians and the humanities?

Harari: More and more disciplines are being politicized, including disciplines that thought they were completely immune to this problem. People in the natural sciences sometimes think that politicization is a problem limited to the humanities and social sciences. They are wrong. We saw it most recently during the pandemic – in epidemiology and medicine – when Covid-related research became highly politicized, and professors found themselves neck-deep in fierce political debates and threatening confrontations. The same has happened in the field of environmental sciences, as climate change has shifted from scientific theory to a hot political topic. We also see it in computer science, which is changing the job market, daily life, and the geopolitical balance of power in the world.

Otmazgin: Would you say that the politicization of academia is inevitable?

Harari: I would say that it is not accidental. It’s the result of science having become the most important change factor of the 21st century. The theories being developed within the university, and the technology emerging from the labs, are changing the world. For better or for worse, scientific debates just cannot be confined within the walls of academia. Nowadays there’s a direct line from the computer science department to the Knesset, the Supreme Court, and the military. It’s therefore unreasonable to expect that the research remain immune to politics. I’d actually like to see political parties drawing up an agenda about algorithms, about AI, about which technologies to develop or not to develop, etc.

Otmazgin: Another pressure we feel within the university is the expectation that we equip our graduates with skills relevant for the global job market, ones that will make them more employable and help them cope with the challenges that await them. What transferable skills do you think our students will need to successfully navigate the job market once they graduate?

Harari: Well, the key problem is that nobody has any idea what the job market will look like in 20 years. This is the first time in history that we are unable to anticipate this. The only thing we know for certain is that it will be completely different from what we see now, and will probably be very surprising. But, what types of jobs people will do in 20 years, and what kind of skills they will need for them, we simply don’t know.

Throughout history, while it was never possible to predict the future, the job market was always relatively stable. 1,000 years ago, in 1022, people couldn’t predict wars and epidemics, but they could confidently anticipate that 20 years forward there would still be a need for farmers skilled in growing food, and soldiers who would know how to ride horses and shoot bows. Those that worked in the royal administration would need to know how to read and write. Yet, when we consider what to teach students today so that they have the relevant skills for 2040 or 2050, we really have no idea. This is a first.

A lot of jobs will completely disappear, a lot of new jobs will emerge, and many existing jobs will evolve. It’s almost impossible to predict how exactly they will change, and therefore we don’t know what particular skills people will need. Take, for example, a skill such as coding. We can comfortably assume that, with the advancement of technology, a lot of code will need to be written over the next few decades. But who’s to say that 20 years from now artificial intelligence won’t be doing the bulk of the coding for us?

Otmazgin: Even if we cannot predict the future job market, how do you think the humanities will fare?

Harari: I believe that philosophy, in particular, will become much more important and applicable in this century. Many complex philosophical questions that, for most of history, had no practical implications for how people actually lived their lives, are becoming practical questions of engineering. The example everybody gives is self-driving vehicles and the need to program ethics into the algorithm. If the vehicle has to compromise the safety of the car owner in order to spare a pedestrian in the middle of the road, how should it proceed? This type of debate turns very old philosophical dilemmas into extremely relevant questions. And, as opposed to philosophers who rarely applied their teachings to reality, algorithms behave precisely as they are programmed. The responsibility is therefore much greater.

Another example is surveillance. Governments throughout history dreamed of monitoring their citizens, but due to technological limitations, it was impossible to monitor everybody all the time. Now, for the first time in history, it is becoming possible to completely annihilate privacy. The surveillance tools developed by researchers and students in our university are applied just a few kilometers away – in Issawiya, Anata, and the Shuafat refugee camp – to create an unprecedented surveillance system. These tools are then exported by Israeli security companies to all kinds of regimes throughout the world, sometimes in order to spy on journalists, minorities, human rights activists, and opposition parties. What is our responsibility in this?

At the very least, I think our university should mandate that every student who learns how to develop such technologies be obligated to take courses on ethics, similar to the requirements for medical students.

Finally, in the 21st century we are likely to learn how to use biotechnology to engineer, reengineer, or even manufacture bodies and brains. This is an extremely dangerous development that raises many philosophical, ethical, and spiritual questions, some of which have been pondered by humans for thousands of years without any practical implications. And now that they are becoming so urgent, I believe that in the 21st century the humanities will be more important than ever before.

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